SORCS3 antibody (AA 201-300) (AbBy Fluor® 488)

Catalog No. ABIN1391650

This Rabbit Polyclonal antibody specifically detects SORCS3 in WB, IF (cc) and IF (p). It exhibits reactivity toward Rat.

Quick Overview for SORCS3 antibody (AA 201-300) (AbBy Fluor® 488) (ABIN1391650)

Target: SORCS3 (Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORCS3 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SORCS3 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 201-300

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SORCS3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SORCS3

Target: SORCS3 (Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3))

Alternative Name: SORCS3

Background:

Synonyms: 6330404A12Rik, KIAA1059, RP11 107L7.1, SORC3_HUMAN, SORCS 3, SORCS, SORCS3, Sortilin related VPS10 domain containing receptor 3, VPS10 domain containing receptor SorCS3, VPS10 domain receptor protein SORCS 3, VPS10 domain-containing receptor SorCS3.

Background: This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain, the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins, it is not yet known if this encoded protein is also a preproprotein.