CCKAR antibody (AA 161-200) (Biotin)

Catalog No. ABIN1391719

This Rabbit Polyclonal antibody specifically detects CCKAR in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Rat, Mouse and Chicken and has been mentioned in 2+ publications.

Quick Overview for CCKAR antibody (AA 161-200) (Biotin) (ABIN1391719)

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Reactivity: Human, Rat, Mouse, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKAR antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CCKAR Antibody (Biotin)

Binding Specificity: AA 161-200

Cross-Reactivity: Chicken, Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCKAR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

References for anti-CCKAR antibody (Biotin) (ABIN1391719)

El-Kassas, Odemuyiwa, Hajishengallis, Connell, Nashar: "Expression and Regulation of Cholecystokinin Receptor in the Chicken's Immune Organs and Cells." in: Journal of clinical & cellular immunology, Vol. 7, Issue 6, (2016) (PubMed).

Target Details for CCKAR

Target: CCKAR (Cholecystokinin A Receptor (CCKAR))

Alternative Name: CCKAR

Background:

Synonyms: CCK-A, CCK1R, CCKRA, CCK1-R, Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCKAR

Background: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Gene ID: 886

UniProt: P32238

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Feeding Behaviour