GALP antibody (AA 25-84) (Biotin)

Catalog No. ABIN1391791

This Rabbit Polyclonal antibody specifically detects GALP in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for GALP antibody (AA 25-84) (Biotin) (ABIN1391791)

Target: GALP (Galanin-Like Peptide (GALP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALP antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GALP Antibody (Biotin)

Binding Specificity: AA 25-84

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GALP

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GALP

Target: GALP (Galanin-Like Peptide (GALP))

Alternative Name: GALP/Alarin

Background:

Synonyms: Alarin, Alarin splice variant, Galanin like peptide, Galanin like peptide precursor protein, GALP precursor protein, GALP_HUMAN.

Background: The galanin family of proteins are key members for inflammatory processes and cell proliferation, and may function as potential biomarkers for colon cancer. Produced in both neuronal and nonneuronal cells in the skin, members of the galanin family include galanin, galanin-message associated peptide, galanin-like peptide and alarin. GALP, also known as galanin-like peptide, is a 116 amino acid secreted protein belonging to the galanin family. Mainly produced in the arcuate nucleus of the hypothalamus (ARC) and the posterior pituitary, GALP is thought to function in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion. GALP binds to the G-protein coupled galanin receptors, including GALR1, GALR2 and GALR3, and may also play a role in energy metabolism, with significant implications towards obesity. GALP exits as two alternatively spliced isoforms.