SOX6 antibody (AA 1-100) (Biotin)

Catalog No. ABIN1392229

This Rabbit Polyclonal antibody specifically detects SOX6 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for SOX6 antibody (AA 1-100) (Biotin) (ABIN1392229)

Target: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX6 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SOX6 Antibody (Biotin)

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOX6

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SOX6

Target: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Alternative Name: SOX6

Background:

Synonyms: HSSOX 6, HSSOX6, SOX-6 SOX 6, SOX6_HUMAN.

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.