NPEPPS antibody (AA 201-300) (AbBy Fluor® 555)

Catalog No. ABIN1392725

The Rabbit Polyclonal anti-NPEPPS antibody has been validated for IF (cc) and IF (p). It is suitable to detect NPEPPS in samples from Mouse.

Quick Overview for NPEPPS antibody (AA 201-300) (AbBy Fluor® 555) (ABIN1392725)

Target: NPEPPS (Aminopeptidase Puromycin Sensitive (NPEPPS))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPEPPS antibody is conjugated to AbBy Fluor® 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-NPEPPS Antibody (AbBy Fluor® 555)

Binding Specificity: AA 201-300

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NPEPPS

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NPEPPS

Target: NPEPPS (Aminopeptidase Puromycin Sensitive (NPEPPS))

Alternative Name: NPEPPS/PSA

Background:

Synonyms: AAP-S,aminopeptidase puromycin sensitive,Cytosol alanyl aminopeptidase,METALLOPROTEASE 100,METALLOPROTEASE MP100,MP 100,MP100,Npepps,PSA,PSA_HUMAN,Puromycin sensitive aminopeptidase,Puromycin-sensitive aminopeptidase.

Background: Puromycin-sensitive aminopeptidase is a 100 kDa zinc metallopeptidase which degrades neuropeptides by removing amino acid residues from the amino-terminus. The protein is the most abundant aminopeptidase in the brain, however it is not exclusive to that organ. It is localized primarily in the cytoplasm, and plays a role in the metabolism of neuropeptides in nerve terminals and synaptic clefts. The human PSA gene maps to chromosome 17q 2-32.