ATP13A2 antibody (AA 1001-1080) (AbBy Fluor® 350)

Catalog No. ABIN1392867

The AbBy Fluor® 350-conjugated Rabbit Polyclonal anti-ATP13A2 antibody (ABIN1392867) specifically detects ATP13A2 in IF (cc) and IF (p). The antibody is reactive with Rat samples.

Quick Overview for ATP13A2 antibody (AA 1001-1080) (AbBy Fluor® 350) (ABIN1392867)

Target: ATP13A2 (ATPase Type 13A2 (ATP13A2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP13A2 antibody is conjugated to AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ATP13A2 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 1001-1080

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP13A2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ATP13A2

Target: ATP13A2 (ATPase Type 13A2 (ATP13A2))

Alternative Name: PARK9/ATP13A2

Background:

Synonyms: AT132_HUMAN, Atp13a2, ATPase type 13A2, CLN12, HSA9947, KRPPD, PARK9, Probable cation transporting ATPase 13A2, Probable cation-transporting ATPase 13A2, Putative ATPase, RP1-37C10.4.

Background: ATP13A2 is a 1,180 amino acid multi-pass membrane protein that belongs to the P5 subfamily of ATPases which play an important role in the transportation of inorganic cations. Expressed as multiple alternative spliced isoforms, ATP13A2 functions to catalyze the conversion of ATP to ADP and a free phosphate, thereby participating in the active transport of ions across cellular membranes. Defects in the gene encoding ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS), a rare hereditary type of Parkinson?s disease that exhibits juvenile onset and is characterized by neurodegeneration and dementia. The ATP13A2 gene maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.

Pathways: Ribonucleoside Biosynthetic Process