GBA antibody (AbBy Fluor® 647)

Catalog No. ABIN1393272

This anti-GBA antibody is a Rabbit Polyclonal antibody detecting GBA in IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for GBA antibody (AbBy Fluor® 647) (ABIN1393272)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GBA Antibody (AbBy Fluor® 647)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Acid beta-glucosidase

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Alternative Name: GBA/Acid beta-Glucosidase

Background:

Beta-Glucosidase is a predominantly liver enzyme which efficiently hydrolyzes Beta-D-glucoside and Beta-D-galactoside. Defects in Beta-Glucosidase cause Gaucher disease, an inherited condition distinguished by the accumulation of glucosylceramide within the cells of the reticuloendothelial system. Beta-Glucosidase is used in enzyme replacement treatment aimed at treating Gaucher disease. The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial Beta-glucosidases.

Synonyms: Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45 , GBA, Gba protein, GBA1, GC antibody GCase, GCB, GLCM_HUMAN, GLUC, Glucocerebrosidase alt., Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta, acid includes glucosylceramidase, Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase.

Pathways: Cellular Glucan Metabolic Process