DOCK7 antibody (AA 1401-1500) (FITC)

Catalog No. ABIN1393550

The Rabbit Polyclonal anti-DOCK7 antibody has been validated for IF (cc), IF (p). It is suitable to detect DOCK7 in samples from Human, Rat.

Quick Overview for DOCK7 antibody (AA 1401-1500) (FITC) (ABIN1393550)

Target: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK7 antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DOCK7 Antibody (FITC)

Binding Specificity: AA 1401-1500

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOCK7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DOCK7

Target: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Alternative Name: DOCK7

Background:

Synonyms: dedicator of cytokinesis 7, Dedicator of cytokinesis protein 7, Gm430, KIAA1771 , MGC189434, mKIAA1771, RP23 329P19.2, ZIR2, DOCK7_HUMAN.

Background: DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.

Gene ID: 85440

UniProt: Q96N67