RILPL2 antibody (AA 111-211) (Biotin)

Catalog No. ABIN1394239

This Rabbit Polyclonal antibody specifically detects RILPL2 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for RILPL2 antibody (AA 111-211) (Biotin) (ABIN1394239)

Target: RILPL2 (Rab Interacting Lysosomal Protein-Like 2 (RILPL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RILPL2 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RILPL2 Antibody (Biotin)

Binding Specificity: AA 111-211

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RILPL2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RILPL2

Target: RILPL2 (Rab Interacting Lysosomal Protein-Like 2 (RILPL2))

Alternative Name: RILPL2

Background:

Synonyms: FLJ30380, FLJ32372, MGC7036, p40phox-binding protein, Rab-interacting lysosomal protein-like 2, RILP-like protein 2, RILPL2, RIPL2_HUMAN, RLP2, Rab interacting lysosomal protein-like 2.

Background: RILPL2 is a 211 amino acid protein that belongs to the RILPL family. RILPL2 does not regulate lysosomal morphology or distribution. RILPL2 shares 32 % and 18 % amino acid identity with RILPL1 and RILP, respectively. RILPL2 as a novel interacting partner for the actin-based molecular motor MyoVa, and has a novel role for RILPL2 in controlling neuronal morphogenesis. It has been suggested that there is also a novel role for RILPL2 in the regulation of cellular shape and dendritic-spine morphogenesis, probably via the Rac1-Pak pathway. PCR analysis of human tissues detects highest RILPL2 expression in lung, followed by placenta. Lower expression is detected in liver, kidney, pancreas, heart and brain, but no expression is detected in skeletal muscle. The RILPL2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 12q24.31.