GRID1 antibody (AA 501-600) (AbBy Fluor® 350)

Catalog No. ABIN1395129

The AbBy Fluor® 350-conjugated Rabbit Polyclonal anti-GRID1 antibody (ABIN1395129) specifically detects GRID1 in FACS, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for GRID1 antibody (AA 501-600) (AbBy Fluor® 350) (ABIN1395129)

Target: GRID1 (Glutamate Receptor, Ionotropic, delta 1 (GRID1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRID1 antibody is conjugated to AbBy Fluor® 350

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GRID1 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 501-600

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRID1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GRID1

Target: GRID1 (Glutamate Receptor, Ionotropic, delta 1 (GRID1))

Alternative Name: GRID1

Background:

Synonyms: GluR delta 1, GluR delta 1 subunit, GluR delta-1 subunit, Glutamate receptor delta 1 subunit, Glutamate receptor delta-1 subunit, Glutamate receptor ionotropic delta 1, GRID 1, Grid1, GluD1, GRID1_HUMAN, KIAA1220.

Background: Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are divided into two categories, namely NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors consist of seven structurally related subunits, designated GluR-1 to -7, and are primarily responsible for fast excitatory neurotransmissions carried out by glutamate. GluR-delta 1 (Glutamate receptor delta-1 subunit), also known as GRID1, is a multi-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain. Localized to the cell junction and the postsynaptic cell membrane, GluR-delta 1 functions as a glutamate receptor that regulates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity. Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, a chronic and severe brain disorder.

Gene ID: 2894

UniProt: Q9ULK0