ZNF843 antibody (AA 51-160) (Biotin)

Catalog No. ABIN1395895

This Rabbit Polyclonal antibody specifically detects ZNF843 in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ZNF843 antibody (AA 51-160) (Biotin) (ABIN1395895)

Target: ZNF843 (Zinc Finger Protein 843 (ZNF843))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF843 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ZNF843 Antibody (Biotin)

Binding Specificity: AA 51-160

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF843

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ZNF843

Target: ZNF843 (Zinc Finger Protein 843 (ZNF843))

Alternative Name: ZNF843

Background:

Synonyms: Zinc finger protein 843, ZN843_HUMAN, ZNF843.

Background: ZNF843 is a 348 amino acid protein that is encoded by a gene which maps to chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The ZNF843 gene product has been provisionally designated MGC46336 pending further characterization.

Gene ID: 283933