ZNF449 antibody (AA 401-518) (Biotin)

Catalog No. ABIN1395961

This Rabbit Polyclonal antibody specifically detects ZNF449 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for ZNF449 antibody (AA 401-518) (Biotin) (ABIN1395961)

Target: ZNF449 (Zinc Finger Protein 449 (ZNF449))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF449 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ZNF449 Antibody (Biotin)

Binding Specificity: AA 401-518

Predicted Reactivity: Human,Mouse,Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF449

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ZNF449

Target: ZNF449 (Zinc Finger Protein 449 (ZNF449))

Alternative Name: ZNF449

Background:

Synonyms: FLJ23614, OTTHUMP00000024072, Zinc finger and SCAN domain containing protein 19, Zinc finger and SCAN domain-containing protein 19, Zinc finger protein 449, ZN449_HUMAN, ZNF449, ZSCAN19.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF449 is a 518 amino acid protein that contains one SCAN box domain and seven C2H2-type zinc fingers. ZNF449 is ubiquitously expressed and localizes to the nucleus. There are three isoforms of ZNF449 that are produced as a result of alternative splicing events.

Gene ID: 203523