Sorbs2 antibody (AA 401-500) (AbBy Fluor® 647)

Catalog No. ABIN1396985

The Rabbit Polyclonal anti-Sorbs2 antibody is suitable to detect Sorbs2 in samples from Human, Mouse and Rat. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for Sorbs2 antibody (AA 401-500) (AbBy Fluor® 647) (ABIN1396985)

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorbs2 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Sorbs2 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 401-500

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SORBS2/ArgBP2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Alternative Name: SORBS2

Background:

Synonyms: ARGBP2, PRO618, Sorbin and SH3 domain-containing protein 2, Arg/Abl-interacting protein 2, Sorbin, SORBS2, KIAA777

Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Gene ID: 8470

UniProt: O94875