HIV-1 Gag antibody (AA 351-450) (Biotin)

Catalog No. ABIN1397220

This anti-HIV-1 Gag antibody is a Rabbit Polyclonal antibody detecting HIV-1 Gag in ELISA, IHC (fro) and IHC (p). Suitable for Human Immunodeficiency Virus (HIV) and Virus.

Quick Overview for HIV-1 Gag antibody (AA 351-450) (Biotin) (ABIN1397220)

Target: HIV-1 Gag (GAG_HIV) (HIV-1 Gag Polyprotein (GAG_HIV))

Reactivity: Human Immunodeficiency Virus (HIV), Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIV-1 Gag antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HIV-1 Gag Antibody (Biotin)

Binding Specificity: AA 351-450

Specificity: This antibody will recognize the full Gag protein and Nucleocapsid protein p7 after cleavage

Cross-Reactivity: Virus

Cross-Reactivity (Details): HIV

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from HIV1 Nucleocapsid protein p7

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HIV-1 Gag

Target: HIV-1 Gag (GAG_HIV) (HIV-1 Gag Polyprotein (GAG_HIV))

Alternative Name: HIV1 Gag Protein

Target Type: Viral Protein

Background:

Synonyms: HIV1 Pr55Gag, Human immunodeficiency virus 1, Gag protein, Nucleocapsid protein p7,

Background: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.