CA11 antibody (AA 101-200) (Biotin)

Catalog No. ABIN1398031

This Rabbit Polyclonal antibody specifically detects CA11 in ELISA, WB, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CA11 antibody (AA 101-200) (Biotin) (ABIN1398031)

Target: CA11 (Carbonic Anhydrase XI (CA11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA11 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CA11 Antibody (Biotin)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CA XI/Carbonic Anhydrase XI

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CA11

Target: CA11 (Carbonic Anhydrase XI (CA11))

Alternative Name: CA11

Background:

Synonyms: CA-RP II, CA-RP XI, CA-XI, CA11, CAH11_HUMAN, Carbonic anhydrase-related protein 11, Carbonic anhydrase-related protein 2, CARP XI, CARP-2, CARP2.

Background: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XI, also referred to as carbonic anhydrase-related protein 11 precursor (CA-RP XI) or carbonic anhydrase-related protein 2 (CA-RP II), is a member of the carbonic anhydrase family that lacks two of the three Zn-binding motifs essential for carbonic anhydrase activity. For this reason, CA XI does not exhibit catalytic activity. It is expressed primarily in brain but is also found in spinal cord and thyroid. CA XI may play a role in brain development.Tissue specificity:Expressed abundantly in the brain with moderate expression also present in spinal cord and thyroid.

Gene ID: 770