HAGHL antibody (AA 1-100) (Biotin)

Catalog No. ABIN1398949

This Rabbit Polyclonal antibody specifically detects HAGHL in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for HAGHL antibody (AA 1-100) (Biotin) (ABIN1398949)

Target: HAGHL (Hydroxyacylglutathione Hydrolase-Like (HAGHL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAGHL antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HAGHL Antibody (Biotin)

Binding Specificity: AA 1-100

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HAGHL

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HAGHL

Target: HAGHL (Hydroxyacylglutathione Hydrolase-Like (HAGHL))

Alternative Name: HAGHL

Background:

Synonyms: HAGHL, HAGHL_HUMAN, Hydroxyacylglutathione hydrolase-like, Hydroxyacylglutathione hydrolase-like protein.

Background: The hydroxyacylglutathione hydrolase-like protein (HAGHL) is a 290 amino acid protein that belongs to the glyoxalase II family. HAGHL binds two zinc ions per subunit and acts as a hydrolase on ester bonds. The gene encoding HAGHL maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Gene ID: 84264