HBB + HBD (AA 51-147) antibody (Biotin)
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- Target
- HBB + HBD
- Binding Specificity
- AA 51-147
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Biotin
- Application
- ELISA, Western Blotting (WB)
- Specificity
- Antibody has equal affinity for Human Hemoglobin Beta and Delta
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Hemoglobin beta
- Isotype
- IgG
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- HBB + HBD
- Background
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Synonyms: CD113t-C, beta-globin, Hemoglobin subunit beta, Hemoglobin beta chain, HBB, Hemoglobin subunit delta, HBD, Delta-globin, Hemoglobin delta chain
Background: The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3 % of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.
- Gene ID
- 3043, 3045
- UniProt
- P68871, P02042
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