GPKOW antibody (AA 121-220) (Biotin)

Catalog No. ABIN1399831

This Rabbit Polyclonal antibody specifically detects GPKOW in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for GPKOW antibody (AA 121-220) (Biotin) (ABIN1399831)

Target: GPKOW (G Patch Domain and KOW Motifs (GPKOW))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPKOW antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPKOW Antibody (Biotin)

Binding Specificity: AA 121-220

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPKOW

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GPKOW

Target: GPKOW (G Patch Domain and KOW Motifs (GPKOW))

Alternative Name: GPKOW

Background:

Synonyms: G patch domain and KOW mots, G patch domain and KOW mots containing protein, G patch domain and KOW mots-containing protein, G patch domain containing 5, G patch domain containing protein 5, G patch domain-containing protein 5, GPATC5, GPATCH5, gpkow, GPKOW_HUMAN, Protein MOS2 homolog, Protein T54, SPP2, T54 antibody T54 protein.

Background: GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.

Gene ID: 27238