CDK5RAP1 antibody (FITC)

Catalog No. ABIN1400696

The Rabbit Polyclonal anti-CDK5RAP1 antibody is suitable to detect CDK5RAP1 in samples from Human, Rat and Mouse. It has been validated for WB and IF (p).

Quick Overview for CDK5RAP1 antibody (FITC) (ABIN1400696)

Target: CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5RAP1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CDK5RAP1 Antibody (FITC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDK5RAP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDK5RAP1

Target: CDK5RAP1 (CDK5 Regulatory Subunit Associated Protein 1 (CDK5RAP1))

Alternative Name: CDK5RAP1

Background:

Synonyms: CDK5 activator binding protein C42 like, CDK5 regulatory subunit associated protein 1, CDK5RAP1.3, CDK5RAP1.4, CGI 05, HSPC167, C20orf34 antibody C42, CDK5 activator binding protein C42, CK5P1_HUMAN.

Background: Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP1 contains one TRAM domain, which is thought to bind tRNA and deliver the RNA-modifying enzymatic domain to its target. There are 4 named isoforms of CDK5RAP1 that are produced as a result of alternative splicing events and are expressed at high levels in heart and skeletal muscle.

Gene ID: 51654