CSPP1 antibody (Biotin)

Catalog No. ABIN1401469

This Rabbit Polyclonal antibody specifically detects CSPP1 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CSPP1 antibody (Biotin) (ABIN1401469)

Target: CSPP1 (Cspp1) (Centrosome and Spindle Pole Associated Protein 1 (Cspp1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSPP1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CSPP1 Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSPP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CSPP1

Target: CSPP1 (Cspp1) (Centrosome and Spindle Pole Associated Protein 1 (Cspp1))

Alternative Name: CSPP1

Background:

Synonyms: Centrosome and spindle pole associated protein 1, CSPP 1, CSPP, FLJ22490, FLJ38886, CSPP1_HUMAN.

Background: Centrosomes are dynamic organelles involved in many aspects of cell function and growth. Centrosomes act as microtubule organizing centers, and provide a site for concerted regulation of cell cycle progression. Duplication of centrosomes occurs once during each cell cycle and requires proper mitotic spindle formation and chromosome segregation. Defects in centrosome duplication or function are linked to many human diseases, including various forms of cancer. The centrosome and spindle pole-associated protein 1 (CSPP1) interacts with centrosomes and microtubules and may play a role in the regulation of G(1)/S-phase progression and spindle assembly. Two isoforms of CSPP1 exist as a result of alternative splicing events. Isoform 1 expression increases throughout the cell cycle and peaks in G2/M phase, whereas isoform 2 expression is highest in G1 phase and decreases thereafter.

Gene ID: 79848