MEAF6 antibody (Biotin)

Catalog No. ABIN1401535

This Rabbit Polyclonal antibody specifically detects MEAF6 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MEAF6 antibody (Biotin) (ABIN1401535)

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEAF6 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MEAF6 Antibody (Biotin)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf149

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MEAF6

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Alternative Name: C1orf149

Background:

Synonyms: CDABP0189, Chromosome 1 open reading frame 149, Eaf6, FLJ11730, Hypothetical protein LOC64769, NY SAR 91, RP3 423B22.2, Sarcoma antigen NY SAR 91, EAF6_HUMAN.

Background: MEAF6, also known as Eaf6 or NY-SAR-91, is a 191 amino acid nuclear protein belonging to the EAF6 family. MEAF6 is a component of the NuA4 histone acetyltransferase complex, which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The gene encoding MEAF6 localizes to chromosome 1 and, due to alternative splicing events, MEAF6 exists in at least three isoforms. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1 such as Hutchinson-Gilford progeria, Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.

Gene ID: 64769