SRF antibody (pSer77) (Biotin)

Catalog No. ABIN1403587

This Rabbit Polyclonal antibody specifically detects SRF in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SRF antibody (pSer77) (Biotin) (ABIN1403587)

Target: SRF (Serum Response Factor (SRF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRF antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SRF Antibody (Biotin)

Binding Specificity: pSer77

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SRF around the phosphorylation site of Ser77

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SRF

Target: SRF (Serum Response Factor (SRF))

Alternative Name: SRF

Background:

Synonyms: Serum Response Factor SRF phospho S77, SRF phospho Ser77, P-SRF Ser77, c fos serum response element binding factor, Serum Response Factor SRF, c fos serum response element binding transcription factor, ELK3, ERP, MCM 1, MCM-1, MCM1, OTTHUMP00000039820, SAP2, Serum response factor, SRF, SRF serum response factor c fos serum response element binding transcription factor, SRF_HUMAN.

Background: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].

Gene ID: 6722