TSSK6 antibody (AbBy Fluor® 555)

Catalog No. ABIN1404353

The Rabbit Polyclonal anti-TSSK6 antibody has been validated for WB and IF (p). It is suitable to detect TSSK6 in samples from Human, Mouse and Rat.

Quick Overview for TSSK6 antibody (AbBy Fluor® 555) (ABIN1404353)

Target: TSSK6 (Testis-Specific Serine Kinase 6 (TSSK6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSSK6 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TSSK6 Antibody (AbBy Fluor® 555)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSSK6/CT72

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSSK6

Target: TSSK6 (Testis-Specific Serine Kinase 6 (TSSK6))

Alternative Name: TSSK6

Background:

Synonyms: Cancer/testis antigen 72, CT72, EC 2.7.11.1, Serine/threonine-protein kinase SSTK, Small serine/threonine kinase, Small serine/threonine protein kinase, SSTK, testis-specic serine kinase 6, Testis-specic serine/threonine kinase 6, Testis-specic serine/threonine-protein kinase 6, TSK 6, TSSK4, TSSK6_HUMAN.

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.

Gene ID: 83983