ANKMY1 antibody (Biotin)

Catalog No. ABIN1404415

This Rabbit Polyclonal antibody specifically detects ANKMY1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ANKMY1 antibody (Biotin) (ABIN1404415)

Target: ANKMY1 (Ankyrin Repeat and MYND Domain Containing 1 (ANKMY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKMY1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ANKMY1 Antibody (Biotin)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKMY1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ANKMY1

Target: ANKMY1 (Ankyrin Repeat and MYND Domain Containing 1 (ANKMY1))

Alternative Name: ANKMY1

Background:

Synonyms: ankyrin repeat and MYND domain containing 1, Testis specic ankyrin like protein 1, TSAL1, Zinc finger MYND domain containing protein 13, ZMYND13, ANKY1_HUMAN.

Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions. Three isoforms of ANKMY1 exists due to alternative splicing events.

Gene ID: 51281