Stathmin 1 antibody (pSer63) (Biotin)

Catalog No. ABIN1404529

This Rabbit Polyclonal antibody specifically detects Stathmin 1 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Stathmin 1 antibody (pSer63) (Biotin) (ABIN1404529)

Target: Stathmin 1 (STMN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stathmin 1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Stathmin 1 Antibody (Biotin)

Binding Specificity: pSer63

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Stathmin 1 around the phosphorylation site of Ser63

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background:

Synonyms: Stathmin 1 Ser63, p-Stathmin 1 Ser63, Lag, LAP 18, LAP18, Leukemia associated phosphoprotein p18, Metablastin, Oncoprotein 18, OP 18, OP18, p18, p19, Phosphoprotein 19, Phosphoprotein p19, PP17, PP19, PR22, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin, Stathmin1, STMN 1, STMN1.

Background: This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID: 3925

Pathways: MAPK Signaling, Microtubule Dynamics