MAP1B antibody (AA 451-550) (HRP)

Catalog No. ABIN1406738

The Rabbit Polyclonal anti-MAP1B antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect MAP1B in samples from Human, Mouse and Rat.

Quick Overview for MAP1B antibody (AA 451-550) (HRP) (ABIN1406738)

Target: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1B antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAP1B Antibody (HRP)

Binding Specificity: AA 451-550

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MAP1B

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAP1B

Target: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Alternative Name: MAP1B

Background:

Synonyms: MAP5, FUTSCH, PPP1R102, Microtubule-associated protein 1B, MAP-1B, MAP1B

Background: Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

Gene ID: 4131

UniProt: P46821

Pathways: Microtubule Dynamics, Regulation of Cell Size