Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (AA 161-260) antibody (HRP)

Catalog No. ABIN1406756

The Rabbit Polyclonal anti- antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect in samples from Human and Rat.

Quick Overview for Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (AA 161-260) antibody (HRP) (ABIN1406756)

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details

Binding Specificity: AA 161-260

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STAU2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Alternative Name: STAU2

Background:

Synonyms: Double stranded RNA binding protein Staufen homolog 2, MGC119606, STAU 2, STAU2, STAU-2, Staufen Drosophila, RNA-binding protein homolog 2, Staufen homolog 2, Staufen RNA binding protein homolog 2, Staufen, RNA binding protein, homolog 2 Drosophila, 39K2, 39K3, DKFZp781K0371, STAU2_HUMAN.

Background: Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5 % and 59.9 % similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.