Protocadherin 8 antibody (AA 51-150) (HRP)

Catalog No. ABIN1407248

The Rabbit Polyclonal anti-Protocadherin 8 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect Protocadherin 8 in samples from Human.

Quick Overview for Protocadherin 8 antibody (AA 51-150) (HRP) (ABIN1407248)

Target: Protocadherin 8 (PCDH8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Protocadherin 8 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Protocadherin 8 Antibody (HRP)

Binding Specificity: AA 51-150

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Rabbit,Chimpanzee,Goose

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDH8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Protocadherin 8

Target: Protocadherin 8 (PCDH8)

Alternative Name: PCDH8

Background:

Synonyms: PAPC, ARCADLIN, Protocadherin-8, PCDH8

Background: Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity).

Gene ID: 5100

UniProt: O95206