Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 251-350) antibody (HRP)

Catalog No. ABIN1407518

The Rabbit Polyclonal anti- antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect in samples from Human.

Quick Overview for Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 251-350) antibody (HRP) (ABIN1407518)

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details

Binding Specificity: AA 251-350

Predicted Reactivity: Human,Mouse,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHGC3/PCDH2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Alternative Name: PCDHGC3/PCDH2

Background:

Synonyms: Cadherin like 2, PC 43, PC43, PCDH 2, PCDH gamma C3, PCDH2, PCDHGC 3, Protocadherin 2, Protocadherin 43, Protocadherin gamma C3, Protocadherin gamma subfamily C 3, Protocadherin43, PCDGK_HUMAN.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH2 (protocadherin-2), also known as PCDHGC3 (protocadherin gamma subfamily C, 3) or PC43, is a 934 amino acid single-pass type I membrane protein that contains six cadherin domains and belongs to the protocadherin gamma family. Functioning as a calcium-dependent cell-adhesion protein, PCDH2 is thought to be involved in the establishment and maintenance of neuronal connections within the brain. Multiple isoforms of PCDH2 exist due to alternative splicing events.