HOXA3 antibody (AA 201-300) (Cy5)

Catalog No. ABIN1408294

This Rabbit Polyclonal antibody specifically detects HOXA3 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for HOXA3 antibody (AA 201-300) (Cy5) (ABIN1408294)

Target: HOXA3 (Homeobox A3 (HOXA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA3 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HOXA3 Antibody (Cy5)

Binding Specificity: AA 201-300

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXA3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HOXA3

Target: HOXA3 (Homeobox A3 (HOXA3))

Alternative Name: HOXA3

Background:

Synonyms: Homeo box 1E, Homeo box A3, Homeobox 1E, Homeobox A3, Homeobox protein HOX A3, Homeobox protein Hox-1E, Homeobox protein Hox-A3, Homeobox protein HOXA3, Homeobox1E, HomeoboxA3, HOX 1, Hox 1.5 like protein, HOX 1E, HOX A3, HOX1, Hox1.5, Hox1.5 like protein, HOX1E, HOXA 3, HOXA3, HXA3_HUMAN, MGC10155.

Background: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. HOX genes that occupy the same relative position along the 5? to 3? coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome. HoxA3, in conjunction with Pax1, mediates the development of the thymus, parathyroid gland, and carotid body. Its expression in the third pharyngeal arch and pouch is required for development of the third arch artery, and homozygous null HoxA3 mutants lack the carotid body. HoxA3 also regulates hindbrain development by controlling the axon projection pattern of motor neurons and sensory neurons of the proximal and distal ganglia.