IL2 Receptor beta antibody (pTyr364) (Cy5.5)

Catalog No. ABIN1408343

The Rabbit Polyclonal anti-IL2 Receptor beta antibody has been validated for WB, IF (p) and IF (cc). It is suitable to detect IL2 Receptor beta in samples from Human.

Quick Overview for IL2 Receptor beta antibody (pTyr364) (Cy5.5) (ABIN1408343)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL2 Receptor beta antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-IL2 Receptor beta Antibody (Cy5.5)

Binding Specificity: pTyr364

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human IL2 Receptor beta around the phosphorylation site of Tyr364

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Alternative Name: IL2 Receptor beta

Background:

Synonyms: Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, p75, IL2RB

Background: IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132. This receptor chain, which is also shared by the IL15 receptor, is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, respectively. CD122 levels can be upregulated by activation stimuli such as IL2.

Gene ID: 3560

Pathways: JAK-STAT Signaling, Growth Factor Binding