RIMS4 antibody (AA 1-100) (HRP)

Catalog No. ABIN1408706

The Rabbit Polyclonal anti-RIMS4 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect RIMS4 in samples from Human.

Quick Overview for RIMS4 antibody (AA 1-100) (HRP) (ABIN1408706)

Target: RIMS4 (Regulating Synaptic Membrane Exocytosis 4 (RIMS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIMS4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RIMS4 Antibody (HRP)

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RIMS4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RIMS4

Target: RIMS4 (Regulating Synaptic Membrane Exocytosis 4 (RIMS4))

Alternative Name: RIMS4

Background:

Synonyms: C20orf190, dJ781B1.3, Rab3-interacting molecule 4, regulating synaptic membrane exocytosis 4, Regulating synaptic membrane exocytosis protein 4, RIM 4, RIM4 gamma, Rims4, RIMS4_HUMAN.

Background: Rim4 (Rab 3 interacting molecule 4), also known as Rim4 or regulating synaptic membrane exocytosis protein 4, is a 269 amino acid protein that localizes to the cell junction and regulates synaptic membrane exocytosis.Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis. Rab 3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (Rab 3 interacting molecule), a putative effector protein for Rab 3 proteins, is thought to regulate neutrotransmitter release through its interaction with Rab 3 and other synaptic proteins.

Gene ID: 140730

Pathways: Synaptic Vesicle Exocytosis