FOXD3 antibody (AA 151-230) (HRP)

Catalog No. ABIN1409636

The Rabbit Polyclonal anti-FOXD3 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect FOXD3 in samples from Human and Mouse.

Quick Overview for FOXD3 antibody (AA 151-230) (HRP) (ABIN1409636)

Target: FOXD3 (Forkhead Box D3 (FOXD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXD3 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FOXD3 Antibody (HRP)

Binding Specificity: AA 151-230

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXD3

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FOXD3

Target: FOXD3 (Forkhead Box D3 (FOXD3))

Alternative Name: FOXD3

Background:

Synonyms: Forkhead box protein D3, HNF3/FH transcription factor genesis, HFH2

Background: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

Gene ID: 27022

UniProt: Q9UJU5