FOXD3 antibody (AA 151-230)

Catalog No. ABIN1387475

The Rabbit Polyclonal anti-FOXD3 antibody is suitable to detect FOXD3 in samples from Human. It has been validated for IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for FOXD3 antibody (AA 151-230) (ABIN1387475)

Target: FOXD3 (Forkhead Box D3 (FOXD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXD3 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FOXD3 Antibody

Binding Specificity: AA 151-230

Purpose: FOXD3 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXD3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FOXD3

Target: FOXD3 (Forkhead Box D3 (FOXD3))

Alternative Name: FOXD3

Background:

Synonyms: Forkhead box protein D3, HNF3/FH transcription factor genesis, HFH2

Background: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

Gene ID: 27022

UniProt: Q9UJU5