LZIC antibody (AA 31-130) (Cy5)

Catalog No. ABIN1410346

This Rabbit Polyclonal antibody specifically detects LZIC in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for LZIC antibody (AA 31-130) (Cy5) (ABIN1410346)

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZIC antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-LZIC Antibody (Cy5)

Binding Specificity: AA 31-130

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LZIC

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LZIC

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Alternative Name: LZIC

Background:

Synonyms: Leucine zipper and CTNNBIP1 domain containing protein, Leucine zipper and ICAT homologous domain containing protein, leucine zipper domain and ICAT homologous domain containing, LZIC antibodyprotein LZIC, LZIC_HUMAN.

Background: LZIC is a 190 amino acid protein that belongs to the CTNNBIP1 family. Ubiquitously expressed, LZIC is found at highest levels in kidney and is upregulated in a few gastric carcinomas. The gene encoding LZIC maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.