SULT4A1 antibody (AA 221-284) (Cy3)

Catalog No. ABIN1411065

This anti-SULT4A1 antibody is a Rabbit Polyclonal antibody detecting SULT4A1 in WB, IF (cc) and IF (p). Suitable for Human and Rat.

Quick Overview for SULT4A1 antibody (AA 221-284) (Cy3) (ABIN1411065)

Target: SULT4A1 (Sulfotransferase Family 4A, Member 1 (SULT4A1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SULT4A1 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SULT4A1 Antibody (Cy3)

Binding Specificity: AA 221-284

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SULT4A1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SULT4A1

Target: SULT4A1 (Sulfotransferase Family 4A, Member 1 (SULT4A1))

Alternative Name: SULT4A1

Background:

Synonyms: BR STL 1, Brain sulfotransferase like protein, Brain sulphotransferase like, BRSTL1, hBR STL 1, hBR STL, Nervous system cytosolic sulfotransferase, Nervous system sulfotransferase, NST, Sulfotransferase 4A1, Sulfotransferase family 4A member 1, Sulfotransferase related protein, SULTX3, ST4A1_HUMAN.

Background: Sulfation is an essential conjugation reaction that increases the water solubility of many compounds, thereby influencing their renal excretion and also resulting in the formation of active metabolites. SULT4A1 (sulfotransferase family 4A, member 1), whose alternative names include brain sulfotransferase-like protein, nervous system sulfotransferase, NST, SULTX3, hBR-STL-1, BRSTL1, BR-STL-1, MGC40032 and DJ388M5.3, is a 284 amino acid protein showing cytoplasmic localization. As a member of the sulfotransferase 1 family, SULT4A1 plays a role in elimination of xenobiotics, activation of procarcinogens and regulation of hormones. SULT4A1 is highly expressed in cerebral cortex and frontal lobe, with lower expression in cerebellum, temporal and occipital lobes. Two SULT4A1 isoforms exist to alternative splicing events. The gene encoding SULT4A1 maps to human chromosome 22q13.2, a region which has been implicated in predisposition to schizophrenia.