OPA1 antibody (AA 651-750) (HRP)

Catalog No. ABIN1411076

The Rabbit Polyclonal anti-OPA1 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect OPA1 in samples from Human, Rat, Mouse, Chicken and Rabbit.

Quick Overview for OPA1 antibody (AA 651-750) (HRP) (ABIN1411076)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reactivity: Human, Rat, Mouse, Chicken, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPA1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-OPA1 Antibody (HRP)

Binding Specificity: AA 651-750

Cross-Reactivity: Chicken, Human, Mouse, Rabbit, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Alternative Name: OPA1

Background:

Synonyms: SP17, NYD-SP17, Coiled-coil domain-containing protein 54, Testis development protein NYD-SP17, CCDC54

Background: OPA1 is a 120 kDa protein belonging to the dynamin family. The OPA1 gene has been localized to 3q29. The gene is targeted to mitochondria and is involved in mitochondrial biogenesis. Defects in OPA1 are a cause of optic atrophy type 1. OPA1 is mostly expressed in retina but can also be expressed in brain, testis, heart and skeletal muscle.

Gene ID: 84692

UniProt: Q8NEL0

Pathways: Tube Formation