CSAD antibody (AA 401-493) (Cy7)

Catalog No. ABIN1411422

This anti-CSAD antibody is a Rabbit Polyclonal antibody detecting CSAD in WB, IF (cc) and IF (p). Suitable for Mouse and Rat.

Quick Overview for CSAD antibody (AA 401-493) (Cy7) (ABIN1411422)

Target: CSAD (Cysteine Sulfinic Acid Decarboxylase (CSAD))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSAD antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CSAD Antibody (Cy7)

Binding Specificity: AA 401-493

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSAD

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CSAD

Target: CSAD (Cysteine Sulfinic Acid Decarboxylase (CSAD))

Alternative Name: CSAD

Background:

Synonyms: CSAD, CSAD_HUMAN, CSD, Cysteine sulfinic acid decarboxylase, Cysteine-sulfinate decarboxylase, Sulfinoalanine decarboxylase.

Background: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 51380