CSAD antibody (AA 401-493) (HRP)

Catalog No. ABIN1411424

The Rabbit Polyclonal anti-CSAD antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect CSAD in samples from Mouse and Rat.

Quick Overview for CSAD antibody (AA 401-493) (HRP) (ABIN1411424)

Target: CSAD (Cysteine Sulfinic Acid Decarboxylase (CSAD))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSAD antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CSAD Antibody (HRP)

Binding Specificity: AA 401-493

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSAD

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CSAD

Target: CSAD (Cysteine Sulfinic Acid Decarboxylase (CSAD))

Alternative Name: CSAD

Background:

Synonyms: CSAD, CSAD_HUMAN, CSD, Cysteine sulfinic acid decarboxylase, Cysteine-sulfinate decarboxylase, Sulfinoalanine decarboxylase.

Background: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

Gene ID: 51380