GPR56 antibody (AA 275-350) (HRP)

Catalog No. ABIN1411574

The Rabbit Polyclonal anti-GPR56 antibody has been validated for WB and ELISA. It is suitable to detect GPR56 in samples from Human and Mouse.

Quick Overview for GPR56 antibody (AA 275-350) (HRP) (ABIN1411574)

Target: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR56 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-GPR56 Antibody (HRP)

Binding Specificity: AA 275-350

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR56

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GPR56

Target: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Alternative Name: GPR56

Background:

Synonyms: BFPP, DKFZp781L1398, EGF TM7 like, G protein coupled receptor 56, GPR 56 , Polymicrogyria bilateral frontoparietal, TM7LN4, TM7XN1, TM7XN1 protein, GPR56_HUMAN, ADGRG1, Adhesion G-protein coupled receptor G1.

Background: G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. G-protein coupled receptor 56 (GPR56), also designated TM7XN1 protein, contains one GPS domain. GPR56 plays an important role in cell-cell interactions and is widely expressed, with highest levels detected in brain, heart and thyroid gland. Defects in the gene encoding for GPR56 can cause bilateral frontoparietal polymicrogyria (BFPP) which is characterized by disorganized cortical lamination.

Gene ID: 9289

UniProt: Q9Y653