LHX5 antibody (AA 25-130) (Cy5)

Catalog No. ABIN1411702

This Rabbit Polyclonal antibody specifically detects LHX5 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for LHX5 antibody (AA 25-130) (Cy5) (ABIN1411702)

Target: LHX5 (LIM Homeobox 5 (LHX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LHX5 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-LHX5 Antibody (Cy5)

Binding Specificity: AA 25-130

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LHX5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LHX5

Target: LHX5 (LIM Homeobox 5 (LHX5))

Alternative Name: LHX5

Background:

Synonyms: LHX 5, Lhx5, LHX5_HUMAN, LIM homeobox 5, LIM homeobox protein 5, LIM/homeobox protein Lhx5, MGC129689.

Background: During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The human LHX5 gene maps to chromosome 12q23-q24 and encodes a 402 amino acid protein. The hippocampus contains the neural circuitry, which is crucial for cognitive functions such as learning and memory. LHX5 regulates precursor cell proliferation and neuronal differentiation and migration during hippocampal development.