Neurensin 1 antibody (AA 101-195) (Cy5)

Catalog No. ABIN1411966

This Rabbit Polyclonal antibody specifically detects Neurensin 1 in IF (cc), IF (p). It exhibits reactivity toward Human.

Quick Overview for Neurensin 1 antibody (AA 101-195) (Cy5) (ABIN1411966)

Target: Neurensin 1 (NRSN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurensin 1 antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Neurensin 1 Antibody (Cy5)

Binding Specificity: AA 101-195

Predicted Reactivity: Human,Mouse,Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NRSN1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Neurensin 1

Target: Neurensin 1 (NRSN1)

Alternative Name: NRSN1

Background:

Synonyms: Neurensin-1, Neuro-p24, NRSN1, NRSN1_HUMAN, p24, Vesicular membrane protein of 24 kDa, Vesicular membrane protein p24, VMP.

Background: Neurensin-1 (NRSN1), also designated Vesicular membrane protein of 24 kDa (VMP) or Neuro-p24, is a 195 amino acid multi-pass membrane protein belonging to the VMP family that is involved in the transport of neural organelle transport and in the transduction of nerve signals or in nerve growth. Expressed solely in brain, Neurensin-1 is also thought to play a role in neurite extension. The gene encoding Neurensin-2 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6.