SLITRK6 antibody (AA 201-300) (Cy7)

Catalog No. ABIN1412226

This anti-SLITRK6 antibody is a Rabbit Polyclonal antibody detecting SLITRK6 in IF (cc) and IF (p). Suitable for Human.

Quick Overview for SLITRK6 antibody (AA 201-300) (Cy7) (ABIN1412226)

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK6 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SLITRK6 Antibody (Cy7)

Binding Specificity: AA 201-300

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLITRK6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLITRK6

Target: SLITRK6 (SLIT and NTRK-Like Family, Member 6 (SLITRK6))

Alternative Name: SLITRK6

Background:

Synonyms: 4832410J21Rik, MGC119595, MGC119596, MGC119597, OTTHUMP00000066012, SLIK6_HUMAN, SLIT and NTRK like family member 6, SLIT and NTRK like protein 6, SLIT and NTRK-like protein 6, Slit and trk like 6, Slit and trk like gene 6, SLITRK 6, Slitrk6.

Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic ?/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK6 (SLIT and NTRK-like family, member 6) is an 841 amino acid single-pass type I membrane protein that contains 16 LRR repeats and belongs to the SLITRK family. Expressed at high levels in select brain tissue, as well as in both adult and fetal lung, SLITRK6 functions to suppress neurite outgrowth, playing a role in the regulation of neuronal function. Multiple isoforms of SLITRK6 exist due to alternative splicing events.

Gene ID: 84189

UniProt: Q9H5Y7