KCTD8 antibody (AA 381-473) (Cy7)

Catalog No. ABIN1412976

The Cy7-conjugated Rabbit Polyclonal anti-KCTD8 antibody (ABIN1412976) specifically detects KCTD8 in WB, IF (cc) and IF (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for KCTD8 antibody (AA 381-473) (Cy7) (ABIN1412976)

Target: KCTD8 (Potassium Channel Tetramerisation Domain Containing 8 (KCTD8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD8 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-KCTD8 Antibody (Cy7)

Binding Specificity: AA 381-473

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCTD8

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KCTD8

Target: KCTD8 (Potassium Channel Tetramerisation Domain Containing 8 (KCTD8))

Alternative Name: KCTD8

Background:

Synonyms: BTB/POZ domain-containing protein KCTD8, KCTD8, KCTD8_HUMAN, Potassium channel tetramerisation domain containing 8.

Background: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling