KCTD8 antibody (AA 381-473) (HRP)

Catalog No. ABIN1412978

The Rabbit Polyclonal anti-KCTD8 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect KCTD8 in samples from Human and Mouse.

Quick Overview for KCTD8 antibody (AA 381-473) (HRP) (ABIN1412978)

Target: KCTD8 (Potassium Channel Tetramerisation Domain Containing 8 (KCTD8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD8 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-KCTD8 Antibody (HRP)

Binding Specificity: AA 381-473

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCTD8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KCTD8

Target: KCTD8 (Potassium Channel Tetramerisation Domain Containing 8 (KCTD8))

Alternative Name: KCTD8

Background:

Synonyms: BTB/POZ domain-containing protein KCTD8, KCTD8, KCTD8_HUMAN, Potassium channel tetramerisation domain containing 8.

Background: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling