ZNF263 antibody (AA 182-248) (HRP)

Catalog No. ABIN1413740

The Rabbit Polyclonal anti-ZNF263 antibody has been validated for ELISA, IHC (fro) and IHC (p). It is suitable to detect ZNF263 in samples from Human.

Quick Overview for ZNF263 antibody (AA 182-248) (HRP) (ABIN1413740)

Target: ZNF263 (Zinc Finger Protein 263 (ZNF263))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF263 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ZNF263 Antibody (HRP)

Binding Specificity: AA 182-248

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF263

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZNF263

Target: ZNF263 (Zinc Finger Protein 263 (ZNF263))

Alternative Name: ZNF263

Background:

Synonyms: A8 51, C2 H2 type zinc finger protein, FLJ20216, HF.12, HZF3.1, KOX25, PP838, Zfp113, Zinc finger protein 3 A8 51, Zinc finger protein 3, Zinc finger protein HF.12, Zinc finger protein KOX25, ZN263_HUMAN.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF263 (Zinc finger protein 263), also known as FPM315 or ZKSCAN12 (Zinc finger protein with KRAB and SCAN domains 12), is a 683 amino acid nuclear protein that contains nine C2H2-type zinc fingers, one KRAB domain and one SCAN box domain. ZNF263 acts as a transcriptional repressor in the nucleus and is expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.

Gene ID: 10127