SLC25A28 antibody (AA 271-364) (HRP)

Catalog No. ABIN1415805

This anti-SLC25A28 antibody is a Rabbit Polyclonal antibody detecting SLC25A28 in ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for SLC25A28 antibody (AA 271-364) (HRP) (ABIN1415805)

Target: SLC25A28 (Solute Carrier Family 25, Member 28 (SLC25A28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A28 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SLC25A28 Antibody (HRP)

Binding Specificity: AA 271-364

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Mitoferrin 2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLC25A28

Target: SLC25A28 (Solute Carrier Family 25, Member 28 (SLC25A28))

Alternative Name: Mitoferrin 2

Background:

Synonyms: MFRN2, Mitochondrial iron transporter 2, Mitochondrial RNA splicing protein 3/4, Mitoferrin 2, Mitoferrin2, Mitoferrin-2, MRS3/4, MRS4L, NPD016, Putative mitochondrial solute carrier, MFRN2_HUMAN, SLC25A28.

Background: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.

Gene ID: 81894

UniProt: Q96A46

Pathways: Transition Metal Ion Homeostasis