KLHDC9 antibody (AA 221-320) (HRP)

Catalog No. ABIN1416496

This Rabbit Polyclonal antibody specifically detects KLHDC9 in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for KLHDC9 antibody (AA 221-320) (HRP) (ABIN1416496)

Target: KLHDC9 (Kelch Domain Containing 9 (KLHDC9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHDC9 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KLHDC9 Antibody (HRP)

Binding Specificity: AA 221-320

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KLHDC9

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KLHDC9

Target: KLHDC9 (Kelch Domain Containing 9 (KLHDC9))

Alternative Name: KLHDC9

Background:

Synonyms: KARCA1, Kelch domain containing 9, Kelch domain containing protein 9, Kelch domain-containing protein 9, Kelch/ankyrin repeat containing cyclin A1 interacting protein, Kelch/ankyrin repeat-containing cyclin A1-interacting protein, KLDC9_HUMAN, Klhdc9, MGC33338, RP11-544M22.9.

Background: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Kelch domain-containing protein 9 (KLHDC9), also designated Kelch/ankyrin repeat-containing cyclin A1-interacting protein (KARCA1), contains 3 Kelch repeats and interacts with CCNA1. The gene encoding KLHDC9 maps to chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene ID: 126823