RNF160 antibody (AA 21-120) (HRP)

Catalog No. ABIN1416598

This Rabbit Polyclonal antibody specifically detects RNF160 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RNF160 antibody (AA 21-120) (HRP) (ABIN1416598)

Target: RNF160 (ZNF294) (Zinc Finger Protein 294 (ZNF294))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF160 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RNF160 Antibody (HRP)

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF160/ZNF294

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RNF160

Target: RNF160 (ZNF294) (Zinc Finger Protein 294 (ZNF294))

Alternative Name: RNF160

Background:

Synonyms: RNF160, ZNF294, C21orf10, C21orf98, E3 ubiquitin-protein ligase listerin, RING finger protein 160, Zinc finger protein 294, LTN1, KIAA0714, HSPC087

Background: E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity).

Gene ID: 26046

UniProt: O94822