UBE2W antibody (AA 71-151) (Cy5.5)

Catalog No. ABIN1416649

This Rabbit Polyclonal antibody specifically detects UBE2W in IF (cc) and IF (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for UBE2W antibody (AA 71-151) (Cy5.5) (ABIN1416649)

Target: UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2W antibody is conjugated to Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-UBE2W Antibody (Cy5.5)

Binding Specificity: AA 71-151

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBE2W

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for UBE2W

Target: UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))

Alternative Name: UBE2W

Background:

Synonyms: hUBC 16, hUBC16, Probable ubiquitin conjugating enzyme E2 W, Probable ubiquitin-conjugating enzyme E2 W, UBE 2W, ube2w, UBE2W_HUMAN, Ubiquitin carrier protein W, Ubiquitin conjugating enzyme 16, Ubiquitin conjugating enzyme E2 W, Ubiquitin conjugating enzyme E2W, Ubiquitin protein ligase W, Ubiquitin-protein ligase W, FLJ11011.

Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). As an E2 class enzyme, UBE2W (Ubiquitin-conjugating enzyme E2 W), also known as Ubiquitin carrier protein W, is a 151 amino acid that catalyzes the conjugation of ubiquitin to proteins that are meant for lysosomal degradation. Functioning as a homodimer, UBE2W is widely expressed, with highest levels in testis. There are two isoforms of UBE2W that are produced as a result of alternative splicing events.

Gene ID: 55284